How often does my puppy need to go to the veterinarian for puppy vaccinations?

For starters, the first set of vaccines...I would normally give a puppy between the six and eight-week range for the first set. When they are young and they nurse and they get colostrum from their mothers, the antibodies that they receive from their mom usually last in the 9 to 10 weeks. I'd probably say 10 weeks would be my answer, range before those antibodies start to wane. We don't know that for certain, and it's not really feasible to get a blood sample and send off antibody titers on a six or seven or eight-week-old puppy. So, we normally start them early, just in case they didn't get adequate antibodies.
The second part of that question was how often do they need to be seen for vaccines? I don't give vaccines in puppies any closer than three weeks apart. So, if they had one at, let's just say, seven weeks, the next one I would recommend doing is at 10 weeks. The next one after that would be 13 weeks, no sooner than that. If it's a week or so later because of your schedule or something, that's fine. You just don't want them any closer together than that.
And my rule of thumb at the end of the day is I want them to have a minimum of two sets of vaccines after 10 weeks. That's because, by then, those maternal antibodies are gone. They're making their own antibodies to your vaccine, and they need to see it at least twice to get an adequate response with antibody production.

This is really important. So you’ll start them between six and nine weeks and then every three weeks after that, up until their fourth-round—especially for that parvovirus vaccine. We definitely don't want them to be exposed to unknown environments or unvaccinated dogs even three to four weeks after their last puppy vaccine.

This is where it gets a little bit tricky for some pet owners and puppy owners in particular. Sometimes people come in and say, gosh, I've already got three vaccines. How many more do you get? What matters is the age at which we see your puppy. Hopefully, this will help explain why we give vaccines the way we do. When a puppy is born, the first milk they get from its mama dog is called colostrum. The colostrum is filled with all these antibodies to protect them against different diseases to some degree. We know that antibody protection will start to fade at about six weeks of age, but every puppy's different. So for some puppies, that protection or that immunity might be gone in the next two or three weeks. For another puppy, it might be another six weeks, and we don't know when that immunity is out of their system from that initial milk called the colostrum. But this much we do know. By the time they are 16 weeks of age, virtually all of the antibodies from the mother's milk are gone. So how many vaccines they're going to get depends on at what age we start. That's the reason we give a series of vaccines up until at least the age of 16 weeks and perhaps a little bit beyond. Typically, we'll give the vaccines about once a month, once every four weeks, or every three to five weeks. That is the window for getting the vaccines. Hopefully, that'll give a little bit more clarity as to why we give the vaccines, like distemper parvo, in a sequence as we do.