They can be painful. I try to give the analogy of when we have had a vaccine. You're generally a little sore. The vaccine itself has a needle, so it is going to sting a little bit. Most dogs tolerate it pretty well. And especially if we can distract them with a treat, they don't tend to mind. But they will usually be a little sore and perhaps a little more tired than usual that day. But generally, after that, they bounce back.

As far as that goes, if your dog has had an allergic vaccine reaction before, we will generally give them a Benadryl injection and potentially even a pain injection to try and help minimize that as a possibility.

There can be, just like any vaccines that a human will get. There are risks associated with vaccines. But from our studies, the overall risks do not outweigh the benefits that the vaccines provide. And so, as far as the risks go, you're going to have the possibility of allergic reactions, swelling, or that can be things as far as an actual vaccine-type reaction that can cause some swelling and discomfort down the road. So, there are risks that you have to certainly keep in mind.

It depends on where they are in the schedule. We recommend puppies get a booster vaccine three weeks later, especially if it's a leptospirosis vaccine and they've only had it the one time. If they have missed it, if it's been over that three-week or four-week mark, it's going to be most ideal to give them an additional booster three weeks afterward.

Titers are for dogs with owners who do not wish to have them vaccinated, as perhaps they have had an adverse reaction to a vaccine before. The owner may choose to do that instead of relying on the medications that we give them beforehand to do their job. Sometimes we don't want to trust that. Titers can be a way to test your dog's blood and determine if they have a good immune response with that vaccine that we had previously given them or if the levels are a little too low and they need to get a booster.

So it certainly can be, especially if your dog has never had any problems with vaccines before. So we always like to make sure that your dog has tolerated vaccines well in the past. Still, as far as things go, especially if your dog is fairly good size, we usually don't see any problems giving multiple vaccines, but we don't like to overdo it either. So if your dog's small or has had a problem with vaccines in the past, we will tend to split those up.

There can be variations in the puppy and dog vaccine schedules. As I said, the puppies will be getting that every three weeks, and then they are good for a year after that last booster. And then dogs sometimes will be able to go every three years, depending on the types of vaccines they need. We’ve come to find that some of them last a little bit longer, but as far as your puppies go, you need to make sure you're doing that every three weeks.