How do I clip my guinea pig’s nails? - Brooks-Falls Veterinary Hospital
It can be tough if they have darker nails, but having little trimmers may help. If they're white nails, you want to take the white part and not touch the pink part at all. If they are darker, then you start with tiny bits to make sure that you're not going to hit their skin and make them bleed. If you're uncomfortable or don't have someone to help you hold them, we can do it for you. Otherwise, I think some of the local humane societies have $5 events every couple of weekends, where you can bring in your guinea pig, and they'll trim the nails for you.
Contributed by Molly Kase DVM
from Brook-Falls Veterinary Hospital & Exotic Care, Inc.