Diseases and Conditions: Histopathology Examinations Explained

When you're at the vet's office, you're bound to eventually get hit with a term or two that you don't understand, and histopathology is a likely candidate. The GeniusVets team provides an insightful overview of histopathology, a crucial diagnostic technique involving the microscopic examination of stained tissue samples. Histopathology, abbreviated as histopath, is performed by skilled veterinary pathologists to unravel the underlying disease processes affecting dogs.

Understanding Histopathology

Histopathology involves studying stained tissue samples under a microscope to discern disease characteristics. Staining enhances cell visibility, aiding in diagnosis. Veterinary pathologists analyze the tissue to describe observed changes and provide a diagnosis, offering valuable information for effective treatment and prognosis.

Procedure and Biopsy

Tissue samples, termed biopsies, are obtained from dogs for histopathology. Biopsy techniques vary based on tissue type and location. Simple methods like skin punch biopsies require local anesthesia, while more complex ones, like intestinal biopsies, necessitate general anesthesia. Veterinarians decide the appropriate method based on factors such as invasiveness and risk. After extraction, the biopsy is sent to a pathologist for evaluation.

Importance of Histopathology

Histopathology is a powerful diagnostic tool for distinguishing diseases with similar symptoms. It offers precise disease identification, guiding tailored treatment plans. Some conditions, including congenital, inflammatory, and cancerous diseases, necessitate histopathology for accurate diagnosis. Cancer identification, grading, and prognosis determination are also facilitated through histopathology.

When to Consider Histopathology

Histopathology is recommended when standard diagnostics prove inconclusive or when a definitive diagnosis is essential. It is useful for severe or unusual skin abnormalities, early cancer detection, and unexplained elevations in liver enzymes. However, it should only be pursued if the dog is stable enough for the procedure and if the results impact the treatment plan and prognosis.

Limitations and Errors

While histopathology is valuable, potential errors can occur due to inadequate tissue collection, poor sample preparation, or lack of clinical history. Error rates among pathologists range from 1-10%. Collaboration between veterinarians and pathologists, requesting a second opinion, or employing special stains can enhance accuracy.

Receiving Results

Once histopathology results are available, veterinarians discuss their implications and guide future steps. While outcomes may not always be favorable, precise diagnosis ensures dogs receive optimal care and treatment.

Histopathology is a crucial tool in veterinary medicine, providing a microscopic window into disease processes. It aids in diagnosis, treatment planning, and prognosis determination, allowing dogs to receive tailored care for a healthier life.

Don't have a vet in your area yet? We can help you find a local veterinarian.

If you have more questions, the GeniusVets Telehealth platform will give you unlimited access to text and/or video calls with board-certified veterinarians! To learn more click here.