Are vaccinations painful to my dog? - Advanced Animal Care
They can be painful. I try to give the analogy of when we have had a vaccine. You're generally a little sore. The vaccine itself has a needle, so it is going to sting a little bit. Most dogs tolerate it pretty well. And especially if we can distract them with a treat, they don't tend to mind. But they will usually be a little sore and perhaps a little more tired than usual that day. But generally, after that, they bounce back.
Contributed by Sarah Crank DMV
from Waco Animal Hospital