Diseases and Conditions: Fighting Feline Immunodeficiency Virus (FIV)

Feline Immunodeficiency Virus, or FIV, is a complex and often misunderstood condition in cats. Much like its human counterpart, HIV, FIV can have serious implications for a cat's health. In this article, we'll explore the world of FIV, from diagnosis to management, and provide valuable insights for cat owners.

Unraveling Feline Immunodeficiency Virus (FIV)

FIV, or feline immunodeficiency virus, shares a close relationship with human immunodeficiency virus (HIV). Both are retroviruses, and many general principles applicable to HIV also apply to FIV. FIV leads to AIDS in cats, but there's a lengthy asymptomatic period before AIDS develops. The primary goal is to prolong this asymptomatic phase, allowing affected cats to live fulfilling lives.

Understanding FIV's Impact

The life expectancy of an FIV-positive cat can vary greatly. Approximately 18% of them succumb to the virus within five years of infection. An additional 18% experience illness due to immune suppression within that timeframe. However, many FIV-positive cats remain asymptomatic or experience sporadic illness while living long lives.

How is FIV Diagnosed?

Most often, FIV infection is detected through a screening test performed at a veterinarian's office or as part of a routine blood panel. When a cat tests positive on a screening test, it's advisable to confirm the diagnosis with a different test, such as a PCR test or Western Blot, to increase certainty. Once confirmed, the cat is considered truly infected.

Kittens under six months old may test positive due to antibodies passed from their mother. These kittens should be retested after they reach 6 months of age.

In households with multiple cats, it's crucial to test all cats when one tests positive to identify who's infected and who's not. Although it's generally considered unnecessary to isolate negative and positive cats, introducing new cats should be avoided to prevent fighting and virus transmission.

It's important to note that the FIV vaccine can cause a cat to test positive on both types of tests, making it a less commonly recommended option among veterinarians.

Testing Kittens

Screening kittens for Feline Leukemia Virus and FIV is essential in the adoption process. However, a positive FIV test in a kitten under six months of age can be misleading. Kittens often inherit antibodies from their FIV-positive mother, which can trigger a positive test result. These antibodies take time to wane, so a positive test in a kitten should prompt retesting around the age of six months when most kittens revert to a negative status.

How Does a Cat Get Infected with FIV?

FIV transmission primarily occurs through deep bite wounds that happen during fights. Although other transmission methods exist, they are less common. FIV can be transmitted sexually and through improperly screened blood transfusions. Casual contact, like sharing food bowls or snuggling, is unlikely to result in transmission. Additionally, infected mother cats rarely pass the virus to their kittens. Mother-to-kitten transmission typically requires the mother to be in the early stages of infection. Kittens testing positive for FIV often revert to negative once their mother's antibodies wane.

In a stable household, isolating an FIV-positive cat is generally unnecessary unless it is prone to fighting with other residents. However, introducing new cats should be avoided, as it can lead to fighting and virus transmission.

What to Do After Diagnosis?

Discovering that your cat has FIV necessitates some lifestyle changes to ensure its well-being.

Keeping Your Cat Indoors Only

The responsible course of action after an FIV diagnosis is to keep your cat indoors to prevent the spread of the disease in your community. Indoor confinement is also essential to minimize your cat's exposure to infectious diseases. While cats accustomed to the outdoors may initially protest, it's crucial not to give in. Over time, they will adapt to their new indoor-only life.

Cats that tend to slip out when doors open can be managed by confining them to a closed room when no one is home to prevent their escape.

Avoiding Raw Foods

The popularity of raw food diets for pets should be disregarded for FIV-positive cats. Uncooked foods, especially meats, can harbor parasites and pathogens that an FIV-positive cat may struggle to combat. Stick to well-established and reputable cat food brands.

Vaccination Considerations

The vaccination of FIV-positive cats can be a subject of controversy. Some evidence suggests that vaccinating these cats may activate the virus, although this is based on laboratory studies and not confirmed in actual infected cats. In regions where vaccination is legally required or if your cat ventures outdoors despite recommendations, regular vaccination is advisable. However, for indoor-only cats with no exposure to other cats, vaccination may be unnecessary unless needed for boarding or elective veterinary procedures.

Parasite Control

FIV-positive cats are more susceptible to infections, so it's crucial to maintain effective parasite control. Consult with your veterinarian to determine which parasites are of concern and which products are suitable for your cat.

Immune-Stimulating Agents and Antioxidants

While there are products claiming to stimulate the immune system, many lack robust scientific backing. LTCI, manufactured by TCyte®, is an injectable immunomodulator originally produced for FIV-positive cats. While it's now primarily marketed for dogs with arthritis, it's still available for cats with FIV. Antioxidants, like Superoxide Dismutase, have shown promise in improving immune parameters in FIV-positive cats, although further research is needed.

General Monitoring

FIV-positive cats require closer monitoring. Instead of the usual annual examination, they should undergo check-ups every six months. Annual full blood panels and urinalysis are advisable. Vigilance for any changes in your cat, no matter how subtle, is essential. Even minor changes should be thoroughly investigated.

The Importance of Indoor Living

Keeping your cat indoors is the most significant step in disease prevention. Feline Immunodeficiency Virus is not transmissible to humans in any way.

Considerations for Medications

AZT (Retrovir®) is an antiviral medication used for human HIV treatment. In FIV-positive cats, it may benefit those showing neurologic signs or suffering from stomatitis (oral inflammation). However, AZT should be reserved for when viral infection symptoms appear. Periodic monitoring is essential as AZT can affect red blood cell production but is reversible upon discontinuation.

Caring for Immune-Suppressed Owners

If an owner is also immune-suppressed, it's important to note that immune-suppressed cats and humans don't mix well. Multiple immune-suppressed individuals, whether human or feline, can amplify infectious agent exposure. Ideally, only one immune-suppressed individual should reside in a household.
 

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